Laboratory for preparation of high-purity clinical chemicals.

Characterization of high-purity chemicals for use as clinical laboratory standards.

From the Research Division, J. T. Baker Chemical Co., Phillipsburg, N. J. 08865. 1 Paper IV in the series “The Practical Analysis of High-Purity Chemicals.” Presented at the 22nd National Meeting of the AACC, Buffalo, N.Y., July 1970. Received April22, 1971; accepted June 3, 1971. Calcium carbonate Lithium carbonate Magnesium acetate Potassium chloride Potassium monobasic phosphate Sodium chlor...

Preparation of High-Purity Grade Ammonium Sulfate from Locally Available Products

Clinical chemistry: a challenge for high-purity standards and reagents.

The dynamic interplay between preparation, handling, containment, and analysis of ultrapure chemical standards and reagents for the clinical chemistry laboratory is described. Inorganic as well as organic standards are reviewed. The contamination problems associated with water, acids, and solvents in trace-element analysis are defined and resolved. In addition, less well-known sources of error ...

DNA/RNA preparation for molecular detection.

BACKGROUND Effective upstream preparation of nucleic acid (NA) is important for molecular techniques that detect unique DNA or RNA sequences. The isolated NA should be extracted efficiently and purified away from inhibitors of a downstream molecular assay. CONTENT Many NA sample preparation techniques and commercial kits are available. Techniques for cell lysis and isolation or purification o...

Preparation and preliminary studies of [64Cu]-antiMUC-1 for breast cancer targeting

PR81 is a monoclonal antibody that binds with high affinity to MUC1 that over expressed on breast tumors. PR81 is considered a suitable targeting molecule that was radiolabeled using Cu-64 for positron imaging studies. The monoclonal antibody was conjugated with DOTA moiety and after purification was evaluated for radiochemical purity, immunoreactivity, cell toxicity and structure integrity as ...